Hookworms Hookworms in Humans: Small Parasites, Big Health Impacts Hookworms may be microscopic, but their effects on the human body can be significant if left unaddressed. These parasitic worms primarily affect the digestive system and blood supply, often flying under the radar due to vague or easily overlooked symptoms. 🔍 Where Do Hookworms Come From? Hookworms thrive in warm, moist environments and are most commonly transmitted through: Skin contact with contaminated soil