Oxalate Kidney Stones Oxalate Kidney Stones: What They Are, Why They Form & How to Support Your Body Naturally 💡 Understanding Oxalate Kidney Stones Oxalate kidney stones develop when calcium and oxalates become too concentrated in the urine , forming crystals that eventually harden into stones. Normally, oxalates bind to calcium in the digestive tract and exit through the stool. But when something disrupts this process, oxalates can enter the bloodstream, reach the kidneys