Aluminum in Allergy Shots Understanding Aluminum Adjuvants in Allergy Shots Allergy shots — also known as allergen immunotherapy — are widely used to help individuals reduce sensitivity to environmental triggers like pollen, mold, dust mites, and pet dander. The goal is simple: expose the immune system to small, controlled amounts of allergens so it gradually builds tolerance and reduces symptoms over time. But there’s an ingredient inside many of these injections that has s