Oxalates Many people are aware of oxalates in foods such as spinach or nuts, but few realize that certain molds and microbes produce oxalates as metabolic byproducts , which can significantly influence human health. Oxalates are organic acids that bind minerals like calcium and magnesium , forming crystals. When produced by microbes or molds, oxalates can accumulate in tissues, contributing to mineral imbalances, oxidative stress, and chronic tissue irritation . How Microbial